Cutaneous complication of perinatal hypoxia

Pathology of perinatal hypoxia.

At birth the newborn infant is required to make an abrupt adjustment to a new environment. The most immediate changes required to support extrauterine life are concerned with respiration and the circulation. The infant must be able to expand its lungs fully and at the same time the pulmonary circulation must be adequate for gaseous exchange to occur between the air spaces and the pulmonary capi...

Perinatal Nitric Oxide Therapy Prevents Adverse Effects of Perinatal Hypoxia on the Adult Pulmonary Circulation

Adverse events in utero are associated with the occurrence of chronic diseases in adulthood. We previously demonstrated in mice that perinatal hypoxia resulted in altered pulmonary circulation in adulthood, with a decreased endothelium-dependent relaxation of pulmonary arteries, associated with long-term alterations in the nitric oxide (NO)/cyclic GMP pathway. The present study investigated whe...

Cutaneous metastasis as a complication of hepatic intra-arterial chemotherapy.

A 44 year old man who had a resection for an adenocarcinoma of the tranverse colon was also found to have a metastatic nodule in the right lobe of the liver (segment VI). He underwent a laparotomy, during which an intra-operative ultrasound revealed 2 additional nodules in segments IV and VII. These three lesions were resected, each with 2 cm margin of normal liver. A Portacath (Pharmacia Delti...

Cutaneous blastomycosis as a complication of transthoracic needle aspiration.

A patient with an ill defined density in the left upper lobe underwent transthoracic needle aspiration. A diagnosis of Blastomyces dermatitidis was made from the aspiration. The patient later returned with a cutaneous ulcer at the site of needle aspiration. B dermatitidis was subsequently recovered from the skin lesion.

Cutaneous scrotal fistula as a complication of acute necrotizing pancreatitis